[NN4101]
[iOVS] Intraocular Concentration of Stem Cell Factor/c-KIT and Galectin-1 in Retinal Diseases (2024)
[NN3201]
[AACR Poster] NN3201, A novel c-Kit targeting ADC, exhibits robust preclinical anti-tumor efficacy in SCLC and GIST models (2024)
[Cardiovasc Res.] Stem cell factor and cKIT modulate endothelial glycolysis in hypoxia (2024)
[AACR Poster] In vivo efficacy and preclinical safety profile of NN3201, an anti-cKIT antibody-drug conjugate, for treating SCLC and AML (2023)
[NN2802]
[Mol. Cell. Biochem] A fully human anti‑c‑Kit monoclonal antibody 2G4 inhibits proliferation and degranulation of human mast cells (2022)
[ARVO Poster] The novel function of NN2101, an anti-c-kit antibody, as an inhibitor of HIF via c-kit regulation in ocular neovascular disease (2022)
[AACR poster] An Optimized Preclinical Antibody-Drug Conjugate Against Cancers with cKIT Overexpression or Activating Mutations (2022)
[NN3201-PoC]
[Int. J. Mol. Sci.] Antibody-Drug Conjugate Targeting c-Kit for the Treatment of Small Cell Lung Cancer (2022)
[Mol. Oncol.] A novel anti-c-Kit ADC to treat wild-type and activating-mutant c-Kit-positive tumors (2021)
[Pharmaceutics] A Fully Human Monoclonal Antibody Targeting cKIT Is a Potent Inhibitor of Pathological CNV in Mice (2021)
[ARVO Poster] A Fully Human Monoclonal Antibody Targeting c-KIT is a Potent Inhibitor of Choroidal Neovascularization in a Murine Model (2021)
[IJBIOMAC] Development and characterization of a fully human antibody targeting SCF/c-kit signaling (2020)
[ATVB] SCF (Stem Cell Factor) and cKIT Modulate Pathological Ocular Neovascularization (2019)
[Mol Vis.] Src tyrosine kinase regulates the stem cell factor-induced breakdown of the blood-retinal barrier (2016)
[ATVB] Stem Cell Factor Is a Potent Endothelial Permeability Factor (2014)
[Cardiovasc Res.] Direct and Differential Effects of Stem Cell Factor on the Neovascularization Activity of Endothelial Progenitor Cells (2011)